Monkeypox is primarily affecting humans and animals appearing symptoms include fever, headache, muscle aches, and a distinctive rash that evolves into pustules. It can cause severe complications, especially in immunocompromised individuals.

Early and accurate clinical diagnosis of monkeypox is crucial. Prompt detection allows for timely supportive care and antiviral treatment, improving patient outcomes and reducing complications. Accurate diagnosis distinguishes monkeypox from similar conditions, ensuring appropriate treatment. As a zoonotic disease, timely diagnosis helps identify the source of infection, enabling prevention measures against further animal-to-human transmission.